Browse studies, page 125

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• Quinolone Antibiotics: The Development of Moxifloxacin 2006
• Powerful bactericidal activity of moxifloxacin in human leprosy Antimicrobial Agents and Chemotherapy, 2008
• Hplc-validation of moxifloxacin UTS ePRESS (University of Technology Sydney), 2016
• Synthesis of Moxifloxacin Chinese Journal of Pharmaceuticals, 2004
• Pharmacokinetics and Safety of Moxifloxacin in Children With Multidrug-Resistant Tuberculosis Clinical Infectious Diseases, 2014
• Evaluation of the safety of prophylactic intracameral moxifloxacin in cataract surgery Journal of Cataract & Refractive Surgery, 2008
• The Effect of Moxifloxacin on QTc and Implications for the Design of Thorough QT Studies Clinical Pharmacology & Therapeutics, 2008
• Moxifloxacin and bilateral acute iris transillumination Journal of Ophthalmic Inflammation and Infection, 2013
• Comparative Effects of Moxifloxacin and Clarithromycin on the Normal Intestinal Microflora Scandinavian Journal of Infectious Diseases, 2000
• Activity of and Resistance to Moxifloxacin in Staphylococcus aureus Antimicrobial Agents and Chemotherapy, 2003
• Statistical Characteristics of Moxifloxacin-Induced QTc Effect Journal of Biopharmaceutical Statistics, 2010
• Preclinical safety evaluation of moxifloxacin, a novel fluoroquinolone Journal of Antimicrobial Chemotherapy, 1999
• Moxifloxacin penetration into human gastrointestinal tissues Journal of Antimicrobial Chemotherapy, 2004
• A Review on Moxifloxacin Research Journal of Science and Technology, 2023
• Substitution of Moxifloxacin for Isoniazid during Intensive Phase Treatment of Pulmonary Tuberculosis American Journal of Respiratory and Critical Care Medicine, 2009
• AVELOX (Moxifloxacin) 2017
• Clinical efficacy of moxifloxacin in the treatment of bacterial keratitis: a randomized clinical trial Ophthalmology, 2007
• Treatment of ankylosing spondylitis with moxifloxacin Southern Medical Journal, 2007
• Moxifloxacin Resistance Optometry and Vision Science, 2012
• Moxifloxacin versus Ethambutol in the First 2 Months of Treatment for Pulmonary Tuberculosis American Journal of Respiratory and Critical Care Medicine, 2006
• Intravitreal clearance of moxifloxacin PubMed, 2005
• The microbiology of moxifloxacin Drugs of today, 2000
• Moxifloxacin and Torsade de Pointes Annals of Pharmacotherapy, 2007
• Pharmacokinetics and elimination of moxifloxacin after oral and intravenous administration in man Journal of Antimicrobial Chemotherapy, 1999
• Moxifloxacin in the Therapy of Experimental Pneumococcal Meningitis Antimicrobial Agents and Chemotherapy, 1998
• Moxifloxacin prophylaxis in neutropenic patients Journal of Antimicrobial Chemotherapy, 2006
• Vitreous and Aqueous Penetration of Orally Administered Moxifloxacin in Humans Archives of Ophthalmology, 2006
• Update on the Cardiac Safety of Moxifloxacin Current Drug Safety, 2012
• Clearance of Intravitreal Moxifloxacin Investigative Ophthalmology & Visual Science, 2005
• Profile of Moxifloxacin Drug Interactions Clinical Infectious Diseases, 2001
• The Bactericidal Activity of Moxifloxacin in Patients with Pulmonary Tuberculosis American Journal of Respiratory and Critical Care Medicine, 2003
• Rifampicin Reduces Plasma Concentrations of Moxifloxacin in Patients with Tuberculosis Clinical Infectious Diseases, 2007
• Four-month moxifloxacin-based regimens for drug-sensitive tuberculosis New England Journal of Medicine, 2014
• The role of moxifloxacin in tuberculosis therapy European Respiratory Review, 2016
• Penetration of moxifloxacin into peripheral compartments in humans Antimicrobial Agents and Chemotherapy, 1999
• Four-Month Rifapentine Regimens with or without Moxifloxacin for Tuberculosis New England Journal of Medicine, 2021
• Pharmacokinetics and metabolism of moxifloxacin Drugs of today, 2000
• High-dose rifapentine with moxifloxacin for pulmonary tuberculosis New England Journal of Medicine, 2014
• Comparison of Efficacy and Safety of Tricilest (Norgestimate-ethinyl Estradiol) and Diane-35 (Cyproterone Acetate-ethinyl Estradiol) in the Treatment of Acne Vulgaris ClinicalTrials.gov · COMPLETED, 2005
• A Randomized, 3-Treatment, 3-Period, 6-Sequence, Crossover, Placebo- and Active-Controlled, Double-Blind for ALXN1840 (Open-Label for Moxifloxacin) Thorough QT/QTc Study to Evaluate ALXN1840 on Cardiac Repolarization in Healthy Adults ClinicalTrials.gov · COMPLETED, 2021
• A Three-Way Crossover Study to Evaluate the ECG Effects of Telaglenastat in Healthy Adult Subjects ClinicalTrials.gov · COMPLETED, 2020
• A Randomized, Double-Blind, Placebo- and Positive-Controlled, Single- and Multiple-Dose, 4-Way Crossover Study to Evaluate the Effects of Domperidone on Cardiac Repolarization in Healthy Subjects ClinicalTrials.gov · COMPLETED, 2012
• Impact of Different DAV132 Dose Regimens (From 2 to 22.5 g/Day During 7 Days, Bid and Tid) on the Fecal Moxifloxacin Concentrations and the Intestinal Microbiota of Healthy Volunteers Treated With Moxifloxacin 400 mg/Day During 5 Days ClinicalTrials.gov · COMPLETED, 2016
• A Single-Dose, Randomized, Double-Blind, Placebo- and Positive-Controlled, 4-Way Crossover Study to Evaluate the Effect of LOXO-292 on the QTc Interval in Healthy Adult Subjects ClinicalTrials.gov · COMPLETED, 2019
• Clinical Trial to Investigate the Effect on Corrected QT Interval Prolongation by Psychotropic Drugs in Healthy Korean Adults After a Single Oral Administration of Escitalopram, Quetiapine, and Moxifloxacin ClinicalTrials.gov · COMPLETED, 2014
• A Phase 1, Multicenter, Randomized, Double-blind, Double-dummy, Placebo- and Positive-controlled, 4-period Crossover Study to Evaluate the Effect of a Single Dose of Balinatunfib on Cardiac Repolarization in Healthy Adult Participants ClinicalTrials.gov · COMPLETED, 2026
• Smoking, Sex Hormones, and Pregnancy ClinicalTrials.gov · COMPLETED, 2017
• A Randomized, Multiple Dose, Placebo and Active Controlled 3-way Crossover Study to Investigate the Effects of Esreboxetine on QTc Interval in Healthy Volunteers ClinicalTrials.gov · COMPLETED, 2009
• A Phase 1, Double-blind, Single-dose, Randomized, Placebo and Active-Controlled, Four-Way Crossover Study Evaluating the Effects of Bemnifosbuvir on Cardiac Repolarization in Healthy Adult Subjects ClinicalTrials.gov · COMPLETED, 2023
• The Effects of Oral Contraceptive Pills vs Hormonal Patch on Coagulation Parameters ClinicalTrials.gov · COMPLETED, 2005
• A Thorough QT/QTc Study to Assess the Effects of Androxal in Healthy Male Subjects ClinicalTrials.gov · COMPLETED
• Adjunctive Systemic Administration of Moxifloxacin in the Treatment of Aggressive Periodontitis: Double-blind Controlled Clinical Trial ClinicalTrials.gov · COMPLETED, 2014
• A Randomized, Double Blind, Single Dose, Positive and Placebo Controlled, Crossover Study of the Effects of Inhaled Carmoterol, at the Proposed Therapeutic and Supratherapeutic Doses, on the QTc Intervals in Healthy Subjects ClinicalTrials.gov · COMPLETED, 2008
• A Phase 2 Open-Label Partially Randomized Trial to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide During 8 Weeks of Treatment in Adult Subjects With Newly Diagnosed Drug-Sensitive or Multi Drug-Resistant, Smear-Positive Pulmonary Tuberculosis ClinicalTrials.gov · COMPLETED, 2018
• A Phase 1, Randomized, Double-blind, Placebo- and Positive-controlled, 4-Period Crossover Trial to Assess the Effect of Anagrelide Hydrochloride on QT/QTc Interval in Healthy Men and Women ClinicalTrials.gov · COMPLETED, 2012
• A Randomized, Controlled, Double Blind, Multicenter, Phase 2 Study of the Safety/Tolerability and Efficacy of JNJ-32729463 Compared With Moxifloxacin for the Treatment of Subjects Requiring Hospitalization for Community-Acquired Bacterial Pneumonia (CABP) With a PORT Score of II or Greater ClinicalTrials.gov · TERMINATED, 2011
• A Double-blind, Randomised, Placebo Controlled, Six-way Crossover Study Including an Open-label Positive Control (Moxifloxacin) to Assess the Influence of Via Respimat® Inhaled BI 1744 CL (Single Doses of 10 μg, 20 μg, 30 μg and 50 μg) on the QT/QTc Interval of the ECG in Healthy Male and Female Volunteers ClinicalTrials.gov · COMPLETED
• Thorough QT Study to Evaluate the Effects of Single Doses of Vicadrostat on Cardiac Safety Parameters in Healthy Male and Female Subjects (a Randomized, Placebo-controlled, Double-blind, Five-period Crossover Study With Open-label Moxifloxacin as Positive Control) ClinicalTrials.gov · COMPLETED, 2026
• Treatment of Keratoconus With Pachymetry Assisted Laser Keratoplasty (PALK) Versus Penetrating Keratoplasty (PK) ClinicalTrials.gov · COMPLETED, 2015
• A Phase 1, Randomized, Double-Blind, Placebo and Active Controlled, Parallel Crossover Study to Evaluate the Effect of Repeat Oral Doses of Mirabegron on Cardiac Repolarization in Healthy Male and Female Adult Subjects ClinicalTrials.gov · COMPLETED, 2010
• A Thorough QTc Evaluation of the Effect of Cotadutide on Cardiac Repolarization in Healthy Participants: A Randomized, Double-blind, Placebo-controlled, 3-arm Parallel Study With a Nested Crossover Design for Positive Control With Moxifloxacin Administration ClinicalTrials.gov · TERMINATED, 2023
• A Double-blind, Randomised, Placebo Controlled Study With Two Sequential Two-way Cross-over Parts to Demonstrate That the Influence of Pramipexole up to 4.5 mg Daily on the QT Interval of the ECG in Healthy Male and Female Volunteers is Comparable With Placebo, With a Positive Control (Two-way Cross-over Moxifloxacin Versus Placebo) ClinicalTrials.gov · COMPLETED
• A Phase 1, Randomized, Placebo-and Positive-Controlled Crossover Study to Determine the Effect of Single-Dose GC4419 on QTc Interval in Healthy Volunteers ClinicalTrials.gov · COMPLETED, 2017
• A Randomized, Double-blind, Placebo-controlled, 4-way Crossover Study to Compare the Effects on the Cardiac De- and Repolarization Duration as Well as Other Cardiac Safety Parameters of Two Doses of Oral Lasmiditan (100 mg and 400 mg) With Those of Moxifloxacin (400 mg) and Placebo in Healthy Subjects ClinicalTrials.gov · COMPLETED, 2011
• A Randomized, 2-Part, Crossover Trial to Evaluate the Effect of Carbetocin on the QT/QTc Interval in Healthy Subjects ClinicalTrials.gov · COMPLETED, 2023
• A Phase I, Randomized, Double-Blinded, Placebo- and Moxifloxacin-Controlled, 4-Period Crossover Study to Evaluate the Effect of GSK2140944 on Cardiac Conduction as Assessed by 12-lead Electrocardiogram in Healthy Volunteers ClinicalTrials.gov · COMPLETED, 2015
• Adjuvant Treatment With a mTOR Inhibitor, Rapamune Improves Outcomes of Severe H1N1 Pneumonia With Acute Respiratory Failure ClinicalTrials.gov · COMPLETED, 2011
• Evaluation of the Effects of Sequential Multiple-Dose Regimens of Cariprazine on Cardiac Repolarization in Patients With Schizophrenia ClinicalTrials.gov · COMPLETED, 2012
• Amniotic Membrane Preparation Containing Riboflavin and Moxifloxacin as Therapeutic Adjuvants for Photo-Activated Chromophore Keratitis- Corneal Cross-Linking (PACK-CXL): Materials Development, Preclinical, and Clinical Trials ClinicalTrials.gov · COMPLETED, 2025
• TBTC Study 28: Evaluation of a Moxifloxacin-based, Isoniazid-sparing Regimen for Tuberculosis Treatment ClinicalTrials.gov · COMPLETED, 2007
• A Thorough Corrected QT Interval Trial ClinicalTrials.gov · COMPLETED
• A Single-centre, Randomised, Double-blind, Placebo Controlled Phase I Study in Two Parts: Part A to Assess a Safe and Tolerable Supratherapeutic Dose of TC-5214 After Single Ascending Oral Doses in Healthy Male Subjects, Followed by Part B: A Four-period Double-dummy Crossover Study to Investigate the Effect of 2 Single Doses (Therapeutic and Supratherapeutic) of TC-5214 on the QT/QTc Interval, Compared to Placebo, Using Moxifloxacin (Avelox®) as a Positive Control, in Healthy Male Subjects ClinicalTrials.gov · TERMINATED, 2012
• Steroids for Corneal Ulcers Trial ClinicalTrials.gov · COMPLETED, 2012
• A Randomized, Double-Blind, Placebo and Active-Controlled, Single-Dose, 4-Treatment Crossover Study to Evaluate the Effects of E2609 on QTc Interval in Healthy Subjects ClinicalTrials.gov · COMPLETED, 2014
• A Pragmatic Trial With Optimized Dose of Rifampicin and Moxifloxacin for the Treatment of Drug Susceptible Pulmonary Tuberculosis ClinicalTrials.gov · COMPLETED, 2026
• A Randomized, Double-Blind, Placebo and Moxifloxacin (Open-Label) Controlled, 4-Period, Crossover Study of the Effects of Multiple Oral Doses of ERB-041 on Cardiac Repolarization in Healthy Subjects ClinicalTrials.gov · COMPLETED
• A Randomised, Controlled, Open-Label, Phase II-III Trial to Evaluate the Safety and Efficacy of Regimens Containing Bedaquiline and Pretomanid for the Treatment of Adult Patients With Pulmonary Multidrug Resistant Tuberculosis ClinicalTrials.gov · COMPLETED, 2022
• Evaluation of Possible Effects on the QT/ QTc Interval of Rupatadine in Healthy Volunteers: A Randomised, Parallel, Placebo and Positive Controlled Study ClinicalTrials.gov · COMPLETED, 2005
• A Double-blind, Double-dummy, Randomized, 3-Period Cross-over, Placebo- and Positive-controlled Study to Evaluate the Effect of JNJ-63623872 on Cardiac Repolarization Interval in Healthy Subjects ClinicalTrials.gov · COMPLETED, 2016
• A Phase I, Double-blind, Double-dummy, Randomized, Placebo Controlled and Active Controlled Trial to Evaluate the Effect of TMC278 25 mg Daily at Steady-state and the Effect of Efavirenz (EFV) 600 mg Daily at Steady-state on the QT/QTc Interval, in 2 Randomized Panels of Healthy Volunteers ClinicalTrials.gov · COMPLETED, 2009
• A Phase 1, Randomized, Single-Dose, Positive- and Placebo-Controlled, 3-Way Crossover Study to Evaluate the Effects of Varegacestat on Cardiac Repolarization in Healthy Participants ClinicalTrials.gov · COMPLETED, 2025
• A Multicenter, Randomized, Open-Label, Parallel-Controlled Clinical Study to Evaluate the Efficacy and Safety of Sitafloxacin in Adult Subjects With Acute Exacerbation of Chronic Obstructive Pulmonary Disease ClinicalTrials.gov · COMPLETED, 2024
• A National, Prospective, Randomized, Open Label Study to Assess the Efficacy and Safety of IV/PO Moxifloxacin vs IV Ceftriaxone + IV Azithromycin Followed by PO Amoxicilline/Clavulanate and PO Clarithromycin in Subjects With Community-acquired Pneumonia ClinicalTrials.gov · COMPLETED, 2009
• A Single-center, Randomized, Double-blind (for OPC-61815 and Placebo), Placebo- and Moxifloxacin Positive-controlled, 4-Period Crossover Trial to Evaluate the Effect of Single Intravenous Administration of OPC-61815 at 16 and 32 mg on QT/QTc Interval in Healthy Male Subjects ClinicalTrials.gov · COMPLETED, 2018
• A Single-center, Single-dose, Randomized, Double-blind, Double-dummy, Placebo-controlled, Positive-controlled, Four-way Crossover Study to Investigate the Effect of Danoprevir With Low Dose Ritonavir (DNV/r) on the QT/QTc Interval in Healthy Subjects ClinicalTrials.gov · COMPLETED, 2011
• A Single-center, Randomized, Blinded, Placebo- and Active-controlled Crossover Study to Evaluate the Effect of Saroglitazar Magnesium on the QTc Interval in Healthy Volunteers ClinicalTrials.gov · COMPLETED, 2019
• A Phase 1, Randomized, Partial Double-Blind, Placebo- and Positive-Controlled, Three-way Crossover Study to Evaluate the Effect of MT-7117 on the QT/QTc Interval in Healthy Subjects ClinicalTrials.gov · COMPLETED, 2022
• A Single Ascending Dose, Randomized, Double-Blind, Double-Dummy, Placebo- and Positive Controlled Study to Evaluate the Effect of ACH-0144471 on the QT Interval in Healthy Adult Subjects ClinicalTrials.gov · COMPLETED, 2018
• The Effect of ALKS 5461 on QT Intervals in Healthy Volunteers ClinicalTrials.gov · COMPLETED, 2015
• A Phase 1 Randomized, Double-Blind, Placebo- and Active-Controlled, Parallel Group/Crossover Thorough QT/QTc Study to Evaluate the Effect of a Therapeutic Dose and a Supra-therapeutic Dose of VI-0521 on Cardiac Repolarization in Healthy Male and Female Volunteers ClinicalTrials.gov · COMPLETED, 2009
• A Randomized, Double-Blind, Double-Dummy, Placebo- and Positive- Controlled, Crossover Study to Evaluate the Effect Of WCK 2349 on the QT/QTc Interval in Health Volunteers ClinicalTrials.gov · COMPLETED, 2015
• An Open Label, Balanced, Randomized, Two-treatment, Two-period, Two-sequence, Single Dose, Crossover, Oral Bioequivalence Study of Moxifloxacin Tablets, 400 mg of Dr. Reddy's Laboratories Limited, Comparing With Avelox® Tablets 400 mg of Bayer Healthcare Pharmaceuticals Inc. in Healthy, Adult Human Subjects Under Fasting Conditions ClinicalTrials.gov · COMPLETED, 2012
• A Multiple-Dose, Randomized, Double-Blind, Placebo- and Active-Controlled, Four-Arm, Parallel Group Thorough QT/QTc Study to Evaluate the Electrophysiologic Effects of Sativex ClinicalTrials.gov · COMPLETED, 2008
• A Phase IIb, Open-Label, Randomized Controlled Dose Ranging Multi-Center Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Exposure-Response Relationship of Different Doses of BTZ-043 in Combination With Bedaquiline and Delamanid in Adult Subjects With Newly Diagnosed, Uncomplicated, Drug-sensitive Pulmonary Tuberculosis ClinicalTrials.gov · COMPLETED, 2024
• A Single Blinded Clinical Trial Comparing Polytrim Ophthalmic Solution and Moxifloxacin Ophthalmic Solution for Treatment of Conjunctivitis ClinicalTrials.gov · COMPLETED, 2012
• A Randomized Double-Blinded Crossover Trial to Define the ECG Effects of Mipomersen (ISIS 301012) Using a Therapeutic and Supratherapeutic Dose Compared to Placebo and Moxifloxacin (a Positive Control) in Healthy Men and Women: A Thorough ECG Trial ClinicalTrials.gov · COMPLETED, 2010
• A Single Dose, Double Blind, Randomized, Crossover Placebo- and Moxifloxacin (Open Label)-Controlled Study to Evaluate the Cardiac Effects of a Novel Food Ingredient in Healthy Male Subjects ClinicalTrials.gov · COMPLETED, 2013
• A Double-blind, Randomized, Placebo-controlled, Four-way Crossover Phase 1 Study Including an Open-label Positive Control (Moxifloxacin) to Assess the Effect of Repeated Daily Doses of 10 mg and 30 mg Macitentan on the QT/QTc Interval of the ECG in Healthy Male and Female Subjects ClinicalTrials.gov · COMPLETED, 2011
• A Blinded, Randomized Crossover Trial to Define the ECG Effects of TA-1790 (Avanafil) Using a Single Clinical and a Supratherapeutic Dose Compared to Placebo and Moxifloxacin in Healthy Men: A Thorough ECG Trial ClinicalTrials.gov · COMPLETED, 2009
• A Randomized, Double Blind, Phase II Multicenter Trial to Evaluate the Safety and Efficacy of PRO-157 Ophthalmic Solution in Three Different Dosing Regimen Versus Moxifloxacin Versus Gatifloxacin in Patients With Bacterial Conjunctivitis ClinicalTrials.gov · COMPLETED, 2017