Browse studies, page 8

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• Engineering cell adhesion: Poly-l-lysine-induced micro- and nanoscale surface modifications and their impact on cellular behavior and subcellular spectral signatures Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy, 2025
• Transcriptional Analysis Revealing the Improvement of ε-Poly-L-lysine Production from Intracellular ROS Elevation after Botrytis cinerea Induction Journal of Fungi, 2024
• Preclinical activity of investigational menin inhibitor DSP-5336 (Enzomenib)-based combinations against MLL1-rearranged (MLL-r) or mutant-NPM1 AML models Blood, 2025
• A Short-term Diet High in Carboxymethyl-lysine (CML) Increases Urinary Excretion but Not Serum CML Levels (P12-012-19) Current Developments in Nutrition, 2019
• Evaluate Wound Healing Time and Infection Control Measures Scholars Journal of Applied Medical Sciences, 2025
• Role of angioprotective therapy in comprehensive postoperative rehabilitation of patients with cicatricial and paralytic laryngeal stenosis Russian otorhinolaryngology, 2025
• Safety and Tolerability of AZD0466 As Monotherapy for Patients with Advanced Hematologic Malignancies. Results from a Phase I/II Trial Blood, 2023
• CRISPR‐Cas9 screen reveals that inhibition of enhancer of zeste homolog 2 sensitizes malignant T cells to dimethyl‐fumarate‐induced cell death The FEBS Journal, 2025
• The menin inhibitor revumenib in KMT2A-rearranged or NPM1-mutant leukaemia Nature, 2023
• Association of lysine pathway metabolites with moyamoya disease Clinical Nutrition, 2023
• Abstract LB245: Collagen remodeling promotes a GPCR-mediated mechanosensory immune checkpoint in ADGRG1+ CD8+ T cells and serves as a spatial biomarker of response to immunotherapy Cancer Research, 2026
• Abstract LB360: Targeted degradation of p300 and CBP via antibody-drug conjugate in prostate cancer cells Cancer Research, 2026
• Phase 2 study of the lysine-specific demethylase 1 (LSD1) inhibitor bomedemstat in patients with polycythemia vera (PV) Journal of Clinical Oncology, 2024
• Abstract 6586: ORIC-944, a potent and selective allosteric PRC2 inhibitor with best-in-class properties, demonstrates combination synergy with AR pathway inhibitors in prostate cancer models Cancer Research, 2024
• Covalent-fragment screening of BRD4 identifies a ligandable site orthogonal to the acetyl-lysine binding sites ACS Chemical Biology, 2020
• Identification and Optimization of a Ligand-Efficient Benzoazepinone Bromodomain and Extra Terminal (BET) Family Acetyl-Lysine Mimetic into the Oral Candidate Quality Molecule I-BET432 Journal of Medicinal Chemistry, 2022
• Abstract 452: ORIC-944, a PRC2 inhibitor with best-in-class properties, restores luminal features and restricts adaptation in prostate cancer models, conferring synergy with AR pathway inhibitors Cancer Research, 2025
• BIRC5 Promoter-Driven Nanodrugs Suppress BIRC5-Positive Cancers Independent of ABCB1 Status and IDO1 Expression International Journal of Nanomedicine, 2026
• VLX600 Disrupts Homologous Recombination and Synergizes with PARP Inhibitors and Cisplatin by Inhibiting Histone Lysine Demethylases Molecular Cancer Therapeutics, 2021
• A phase 1 dose escalation and dose optimization study to evaluate the preliminary safety, tolerability, pharmacokinetic, pharmacodynamic, and clinical activity profile of AUTX703 in participants with relapsed/refractory acute myeloid leukemia and myelodysplastic syndromes Blood, 2025
• Abstract CT146: AZD0466 in patients with advanced non-Hodgkin lymphoma: Efficacy and safety in an open-label phase 1 trial Cancer Research, 2024
• Efficacy of Toothpaste Containing Polylysine and Funme Peptide on Oral Microbiome and Oral Health International Dental Journal, 2025
• Therapeutic Immune Modulation Against Solid Cancers with Intratumoral Poly-ICLC: A Pilot Trial Clinical Cancer Research, 2018
• Dietary lysine requirements of older adults stratified by age and sex Journal of NutriLife, 2024
• Mezigdomide is effective alone and in combination with Menin inhibition in pre-clinical models of KMT2A-r and NPM1c AML. Blood, 2023
• A Multi-Site Break through Cancer Trial: Phase II Study Investigating Dual Inhibition of BCL2 and Menin in AML MRD Using the Combination of Venetoclax and Revumenib (Trial In Progress) Blood, 2024
• LP2, a cyclic angiotensin-(1-7) analog extended with an N-terminal D-lysine, impairs growth of patient-derived xenografts of colorectal carcinoma in mice Peptides, 2022
• PS5-09-30: A phase 1/2 trial evaluating the safety, tolerability, and efficacy of the KAT6 inhibitor, PF-07248144, in combination with vepdegestrant in patients with ER+/HER2− locally advanced or metastatic breast cancer Clinical Cancer Research, 2026
• A Comparative Clinical Trial of Lymecycline The British journal of clinical practice, 1965
• Phase 3 study of the lysine-specific demethylase 1 (LSD1) inhibitor bomedemstat in patients with essential thrombocythemia (ET) Journal of Clinical Oncology, 2024
• Relationship between plasma l-lysine concentrations and levels of HIV-1 RNA Virulence, 2013
• Enhancement of Airway Gene Transfer by DNA Nanoparticles Using a pH-Responsive Block Copolymer of Polyethylene Glycol and Poly-L-lysine Biomaterials, 2011
• Autologous Aldrithiol-2-Inactivated HIV-1 Combined with Polyinosinic-polycytidylic acid–poly-L-lysine carboxymethylcellulose as a Vaccine Platform for Therapeutic Dendritic Cell Immunotherapy Vaccine, 2014
• Risk Assessment of "Other Substances" – L-lysine 2020
• A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer Science Translational Medicine, 2016
• Evaluation of a standardised Vi poly-l-lysine ELISA for serology of Vi capsular polysaccharide antibodies Biologicals (Print), 2020
• The clinical and microbiological utility of inhaled aztreonam lysine for the treatment of acute pulmonary exacerbations of cystic fibrosis: An open-label randomised crossover study (AZTEC-CF) Journal of Cystic Fibrosis, 2020
• Resistant Potato Starch Supplementation Increases Serum Antioxidant Levels in a Randomized Trial Metabolites, 2025
• The Use of Poly-L-Lysine as a Capture Agent to Enhance the Detection of Antinuclear Antibodies by ELISA PLoS ONE, 2016
• Clinical experience with L-lysine escinate for acute and chronic cerebral circulatory disorders 2015
• Possibility of orally administered L-lysine-a-oxidase internalization in the model of isolated CUT of RAT small intestine Problems in oncology, 2019
• DIPG-07. Preclinical and case study results underpinning the phase II clinical trial testing the combination of ONC201 and paxalisib for the treatment of patients with diffuse midline glioma (NCT05009992) Neuro-Oncology, 2022
• S4.5b A randomized, double blind phase II proof-of-concept superiority trial of fosravuconazole 200 mg or 300 mg weekly dose versus itraconazole 400 mg daily, all three arms in combination with surgery, in patients with eumycetoma in Sudan—pharmacokinetic results Medical Mycology, 2022
• Development of non-pyrogenic magnetosome minerals coated with poly-l-lysine leading to full disappearance of intracranial U87-Luc glioblastoma in 100% of treated mice using magnetic hyperthermia Biomaterials, 2017
• Steroids and L-Lysine Aescinate for Acute Radiculopathy Due to a Herniated Lumbar Disk Medicina, 2019
• Clinical Evaluation of an NVTIA GABA-Lysine Calcium Preparation for Promoting Calcium Absorption Frontiers in Humanities and Social Sciences, 2026
• Superior bioavailability of EPA and DHA from a L-lysine salt formulation: a randomized, three-way crossover study Food & Nutrition Research, 2024
• Safety of a probiotic cheese containing Lactobacillus plantarum Tensia according to a variety of health indices in different age groups Journal of Dairy Science, 2012
• Relative bioavailability of organic and hydroxy copper sources in growing steers fed a high antagonist diet1 Journal of Animal Science, 2019
• Redução dos níveis de proteína e suplementação aminoacídica em rações para codornas européias (Coturnix coturnix coturnix) 2006
• Effects of in ovo injection of amino acids on hatching performance, cell-mediated immunity and blood profile of FUNAAB Alpha broiler chickens 2020
• Efficacy of lisdexamfetamine dimesylate in children with attention-deficit/hyperactivity disorder previously treated with methylphenidate: a post hoc analysis Child and Adolescent Psychiatry and Mental Health, 2011
• Abstract 6762: Baseline multiomics and chemotherapy efficacy in preclinical trials using patient-derived xenograft models of cholangiocarcinoma can reveal distinct signatures of chemotherapy response Cancer Research, 2025
• Effect of Dietary Lysine Restriction and Energy Density on Performance, Nutrient Digestibility and Meat Quality in Finishing Pigs 2010
• Acute lysine supplementation does not improve hepatic or peripheral insulin sensitivity in older, overweight individuals Nutrition and Metabolism, 2014
• The impact of “super-dosing” phytase in pig diets on growth performance during the nursery and grow-out periods Translational Animal Science, 2018
• A phase 3 study of revumenib plus venetoclax/azacitidine in adults with newly diagnosed NPM1 -mutated or KMT2A -rearranged acute myeloid leukemia ineligible for intensive chemotherapy (EVOLVE-2/HO177/AMLSG35-24/ACT-HOV-AML-002) Journal of Clinical Oncology, 2026
• Dietary advanced glycation end products (AGEs) and breast cancer mortality in the women’s health initiative (WHI) Journal of Clinical Oncology, 2020
• Associations among High-Quality Protein and Energy Intake, Serum Transthyretin, Serum Amino Acids and Linear Growth of Children in Ethiopia Nutrients, 2018
• Nano Zinc Oxide Improves Performance, IGF-I mRNA Expression, Meat Quality, and Humeral Immune Response and Alleviates Oxidative Stress and NF-κB Immunohistochemistry of Broiler Chickens Biological Trace Element Research, 2022
• Effects of replacement of fish meal by poultry by-product meal on growth performance and gene expression involved in protein metabolism for juvenile black sea bream (Acanthoparus schlegelii) 2020
• Local tranexamic acid reduces surgical blood loss Wounds (King of Prussia, Pa.), 2022
• Fibrinolysis and tranexamic acid: mechanistic principles ANZ journal of surgery, 2020
• Effects of dietary supplementation with lysine-yielding Bacillus subtilis on gut morphology, cecal microflora, and intestinal immune response of Linwu ducks Journal of Animal Science, 2015
• Dietary amino acids, macronutrients, vaginal birth, and breastfeeding are associated with the vaginal microbiome in early pregnancy Microbiology spectrum, 2024
• Effects of close-up dietary energy level and supplementing rumen-protected lysine on energy metabolites and milk production in transition cows Journal of Dairy Science, 2019
• Impact of dietary counselling on cardiometabolic health, mental health and dietary quality in Singapore older women NMCD. Nutrition Metabolism and Cardiovascular Diseases, 2025
• Iadademstat and Gilteritinib for the Treatment of FLT3-Mutated Relapsed/Refractory Acute Myeloid Leukemia: The Frida Study Blood, 2023
• Investigating the Impact of Protein Supplementation from Different Sources on Advanced Glycation End Products in Older Adults in Singapore Following a Healthy Dietary Pattern Nutrients, 2026
• Effects of lysine deficiency or excess on growth and the expression of lipid metabolism genes in slow-growing broilers Poultry Science, 2019
• Investigating the Interaction Between a Polyphenol-Rich Mediterranean Diet and Genetic Variants on Advanced Glycation End-Product (AGE) Level Journal of Health, Wellness and Community Research, 2026
• Effect of dietary sesame (Sesame indicum L) seed meal level supplemented with lysine and phytase on performance traits and antioxidant status of late-phase laying hens Asian-Australasian Journal of Animal Sciences, 2019
• Two phase 3 placebo-controlled trials of aztreonam lysine for inhalation (AZLI) for non-cystic fibrosis bronchiectasis (NCFB) European Respiratory Journal, 2013
• The effect of a diet reduction in advanced glycation end products on metabolic markers in patients with chronic coronary artery disease and type 2 diabetes European Heart Journal, 2025
• Circulating nitric oxide pathway metabolites in heart failure with preserved ejection fraction: a sex-stratified cross-sectional analysis Biology of Sex Differences, 2026
• 719-P: Metabolomic Characteristics Associated with Changes in Fasting Blood Glucose in a 12-Month Lifestyle Intervention Trial Diabetes, 2024
• Severe Hypouricemia Impairs Endothelium‐Dependent Vasodilatation and Reduces Blood Pressure in Healthy Young Men: A Randomized, Placebo‐Controlled, and Crossover Study Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2019
• Pulmonary hypertension following L-lysine ibuprofen therapy in a preterm infant with patent ductus arteriosus Canadian Medical Association Journal, 2006
• Blood mRNA biomarkers distinguish variable systemic and sputum inflammation at treatment initiation of inhaled antibiotics in cystic fibrosis: A prospective non-randomized trial PLoS ONE, 2022
• Growth Responses of Hybrid Catfish ( Hetero-clarias ) Juveniles Fed All Plant: Protein Diets Supplemented with L-lysine and L-methionine 2017
• [177Lu]Lu-dota-tate versus sunitinib in patients with metastatic progressive neuroendocrine tumours of the pancreas (OCLURANDOM): a randomised, controlled, phase 2 trial The Lancet Oncology, 2026
• Physical activity and markers of glycation in older individuals: data from a combined cross-sectional and randomized controlled trial (EXAMIN AGE) Clinical science, 2020
• Improvement of skin condition and intestinal microbiota via Heyndrickxia coagulans SANK70258 intake: A placebo-controlled, randomized, double-blind, parallel-group comparative study Nutrition (Burbank, Los Angeles County, Calif.), 2024
• Metabolic plasticity of the gut microbiome in response to diets differing in glycemic load in a randomized, crossover, controlled feeding study American Journal of Clinical Nutrition, 2025
• Two dose levels of once-weekly fosravuconazole versus daily itraconazole in combination with surgery in patients with eumycetoma in Sudan: a randomised, double-blind, phase 2, proof-of-concept superiority trial Lancet. Infectious Diseases (Print), 2024
• E2112: Randomized Phase III Trial of Endocrine Therapy Plus Entinostat or Placebo in Hormone Receptor–Positive Advanced Breast Cancer. A Trial of the ECOG-ACRIN Cancer Research Group Journal of Clinical Oncology, 2021
• A Dietary Supplement in the Management of Patients with Lumbar Osteochondrosis: A Randomized, Double-Blinded, Placebo-Controlled Study Nutrients, 2024
• Effect of dried Ziziphus Jujube Consumption on Plasma Insulin, Blood Pressure, Oxidative Stress, and Advanced Glycation End Products in Diabetic Patients with Excess Weight: A Randomized Controlled Trial International Journal of Preventive Medicine, 2025
• Acute effects of MDMA, MDA, lysine-MDMA, and lysine-MDA in a randomized, double-blind, placebo-controlled, crossover trial in healthy participants Neuropsychopharmacology, 2025
• Efficacy of a mouthwash containing ε-poly-L-lysine, funme peptides and domiphen in reducing halitosis and supragingival plaque: a randomized clinical trial BMC Oral Health, 2024
• The relationships of trehalose and its metabolism to conidiation in Neurospora 1967
• Coexistence of glutamic acid decarboxylase- and somatostatin-like immunoreactivity in neurons of the feline nucleus reticularis thalami Journal of Neuroscience, 1983
• The complexity of coagulopathy pathogenesis in COVID-19 2020
• Use of tranexamic acid in gastrointestinal bleeding and patients with haematological malignancies ANZ journal of surgery, 2020
• Aeromonas : An unusual cause of lower gastrointestinal bleed Indian Journal of Medical Microbiology, 2016
• Re: Cystinuria: Genetic Aspects, Mouse Models, and a New Approach to Therapy Journal of Urology, 2019
• Development of Nanocapsules Containing Cytotoxic Agents- A Review Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal), 2021
• A review of treatment modalities in gyrate atrophy of the choroid and retina (GACR) Molecular Genetics and Metabolism, 2021
• Diet and Psychosis: A Scoping Review Neuropsychobiology, 2018
• Role of Essential Amino Acids in Age-Induced Bone Loss International Journal of Molecular Sciences, 2022