Outcome of Endoscopic Band Ligation in Cases with Gerd Refractory to Once Daily Medical Therapy of Dexlansoprazole
Abstract
: Background: The conventional surgeries for the treatment of gastroesophageal reflux disease (GERD) results in high cost, post-operative complications and also add to our socioeconomic burden. The aim in our study was to study the effectiveness of endoscopic band ligation on symptom relief and quality of life in patients with GERD refractory to once daily medical therapy of Dexlansoprazole, to evaluate the endoscopic response and also to study any adverse effects. Method: Banding was done for the patients having symptoms of GERD despite treatment by dexlansoprazole. They were evaluated before and after treatment using ogdoscopy, 24 hr pH monitoring and GERD HRQoL questionnaires. Result: In our study, 13 cases were selected out of which maximum number of cases was within the age group of 21 to 30 yrs On pre op and post op ph monitoring De Meester score shows marked reduction in the score. On comparative study of pre op GERD HRQoL and post of GERD HRQoL, it shows marked reduction in its value. Out of 13, 5 patients shows normal study in post op endoscopy. Most common finding in post op endoscopy was partially reduced hiatus hernia which was seen in 6 patients and least common finding is post banding fibrosis and concentric ring at esophagogastic region. Conclusion: Endoscopic band ligation proved to be a good treatment choice for GERD Refractory to PPI. Endoscopic band ligation is a safer endoscopic approach and has lower rates of complications and higher rates of resolving…
Read the paper
Related studies
- Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials
- Tocilizumab in patients with severe COVID-19: a retrospective cohort study
- A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study
- Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study
- Are noise and air pollution related to the incidence of dementia? A cohort study in London, England
- Long COVID symptoms and duration in SARS-CoV-2 positive children — a nationwide cohort study
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.