Do Laryngeal Biopsy Findings Predict Treatment Response in Suspected Laryngopharyngeal Reflux
Abstract
The purpose of the study is to determine if tissue changes are predictor of clinical response to therapy.
The hypothesis is that the patients who have laryngeal signs and symptoms related to acid reflux, will have ultrastructural changes on a laryngeal biopsy which are predictors of response to therapy.
Conditions: Larynx Disease, Gastroesophageal Reflux.
Primary outcome: Number of Patients With Dilation of Intracellular Spaces 3 Months After Therapy.
Enrollment: 38 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 38 participants or records.
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