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Quantitative gonioscopic assessment of anterior chamber angle remodeling using the spaeth classification after Schlemm's canal-based MIGS (3T) in POAG: a one-year retrospective study

Yu P, Hu B, He Y, Xin M, Fan H, Jing L, Wang S, Shu J et al.

BMC ophthalmology, 2026

25 participants

Abstract

Background: Trabeculotome Tunneling Trabeculoplasty (3T) is a recently developed Schlemm's canal-based minimally invasive glaucoma surgery (MIGS) designed to reconstruct the trabecular meshwork-Schlemm's canal pathway to facilitate aqueous humor outflow, while minimizing disruption to ocular surface structures. Although this procedure is gaining clinical use in China, evidence regarding its long-term efficacy, safety, and anatomical impact remains limited. Few studies have systematically assessed postoperative changes in the anterior chamber angle, which plays a key role in intraocular pressure (IOP) control. This study aimed to evaluate the 1-year outcomes of 3T surgery in patients with primary open-angle glaucoma (POAG), including its effectiveness, safety profile, and angle remodeling assessed via gonioscopic imaging.

Methods: This retrospective study included 25 patients (31 eyes) with primary open-angle glaucoma (POAG) who underwent Trabeculotome Tunneling Trabeculoplasty (3T) at Chengdu Integrated TCM and Western Medicine Hospital, also known as Chengdu First People's Hospital between December 2022 and October 2023. All patients were followed for 12 months. Clinical data including preoperative and postoperative intraocular pressure (IOP), number of anti-glaucoma medications, intra- and postoperative complications, and gonioscopic findings were collected and analyzed to evaluate the 1-year outcomes of the 3T procedure in terms of efficacy, safety, and anterior chamber…

How strong is the evidence?

Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 25 participants or records.

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