Successful management of Lomentospora prolificans septic arthritis and osteomyelitis in an immunocompetent child: A case report
Abstract
Available online We report a case of limb-threatening Lomentospora prolificans elbow infection in a 3-year-old immunocompetent boy following a closed fracture. Resolution of infection was achieved following combined aggressive debridement, combined antifungal therapy, voriconazole-loaded bone cement, and antiseptic joint irrigation. This highlights the need for early diagnosis and multi-modal surgical, medical and other novel adjunctive therapies in managing these difficult-to-treat infections. Increased research and improved access to novel antifungal drugs are essential to enhance treatment options for intrinsically multidrug-resistant fungal infections.
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Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.
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