Prescription Patterns and Utilization Trends of Proton Pump Inhibitors among Hospitalized Patients in a Tertiary Care Hospital in Bangladesh
Abstract
Background: Proton pump inhibitors (PPIs) are widely used for the management of acid-related gastrointestinal disorders.Despite their effectiveness, inappropriate prescribing regarding indication, dose, and frequency is common, contributing to adverse effects, polypharmacy, and increased healthcare costs.Objective: This study aimed to evaluate the prescription patterns, utilization trends of PPI therapy among hospitalized patients in a tertiary care setting.Methods: A cross-sectional observational study was conducted from July 2022 to June 2023 at Sylhet MAG Osmani Medical College, in collaboration with Sylhet MAG Osmani Medical College Hospital, Sylhet, Bangladesh.A total of 600 patients admitted to the Departments of Medicine, Surgery, Gastroenterology, and Gynecology & Obstetrics and prescribed at least one PPI were included.Data were collected from treatment sheet and patient interviews, focusing on demographics, PPI type, route, dose, frequency, indication, comorbidities, and concomitant medications.Statistical analysis was performed using SPSS.Results: Among 600 patients, 59.8% were female, with a mean age of 42.94 ± 17.16 years.The highest PPI prescription rates were observed in gynecology and obstetrics (94.9%), followed by surgery (92.5%), gastroenterology (86%), and medicine (68.6%).Only 47.8% of prescriptions were indicated appropriately, 61% had correct dosing, and 13.7% had correct frequency; fully appropriate therapy was achieved in 4% of patients.Oral…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 600 participants or records.
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