The Influence of Helicobacter pylori Infection Treatment on Psoriasis Severity
Abstract
Helicobacter pylori infection is a condition caused by the gram-negative bacterium H. pylori affecting the mucous lining of the antrum portion of the stomach. At least 50% of the global population fall victim to this condition with Africans proven to have the highest prevalence rate of 70%, followed by South America and Western Asia with 69.4 and 66.6% respectively. In Africa, Nigeria is said to have the highest prevalence rate of H. pylori infection recording 87.7 to 89.7%. H. pylori infection is known to inflict a wide range of gastric complications including Peptic ulcer disease among others, and extra gastric complications such as Neurological diseases, as well as Dermatological diseases. Psoriasis, an autoimmune chronic inflammatory disease of the skin, affecting more than 100 million individuals globally, is one of the dermatological complications of H. pylori infection. It has been noted that H. pylori seem to play a major role in the development of psoriasis. Therefore, this chapter seeks to provide readers with the connection between H. pylori infection and Psoriasis as well as the influence the treatment of H. pylori infection has on Psoriasis severity.
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