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Quantum dots: synthesis, bioapplications, and toxicity

Alireza Valizadeh, Haleh Mikaeili, Mohammad Samiei, Samad Mussa Farkhani, Nosratollah Zarghami, Mohammad Kouhi, Abolfazl Akbarzadeh, Soodabeh Davaran

Nanoscale Research Letters, 2012

579 citations

Abstract

This review introduces quantum dots (QDs) and explores their properties, synthesis, applications, delivery systems in biology, and their toxicity. QDs are one of the first nanotechnologies to be integrated with the biological sciences and are widely anticipated to eventually find application in a number of commercial consumer and clinical products. They exhibit unique luminescence characteristics and electronic properties such as wide and continuous absorption spectra, narrow emission spectra, and high light stability. The application of QDs, as a new technology for biosystems, has been typically studied on mammalian cells. Due to the small structures of QDs, some physical properties such as optical and electron transport characteristics are quite different from those of the bulk materials.

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