Safety and Efficacy of Lansoprazole in Patients With Reflux Disease. An Open, Single Arm, Long-term Study
Abstract
The purpose of this study is to measure the safety, efficacy and quality of life of lansoprazole in patients with reflux disease over a five year period.
Conditions: Gastroesophageal Reflux.
Primary outcome: Change From Baseline in Reflux Disease Symptom - Heartburn; Change From Baseline in Reflux Disease Symptoms - Acid Regurgitation; Change From Baseline in Reflux Disease Symptom - Difficulty Swallowing; Change From Baseline in Reflux Disease Symptom - Pain in Upper Abdomen; Change From Baseline in Reflux Disease Symptom - Nausea & Vomiting; Change From Baseline in Reflux Disease Symptom - Cough & Sore Throat; Change From Baseline in Endoscopic Healing of Erosive Reflux Disease as Assessed by Endoscopy.
Enrollment: 506 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 506 participants or records.
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