Dyspepsia: An Integrated Review of Diagnosis, Classification, and Mechanisms of Modern and Herbal Medications
Abstract
Dyspepsia is a common and complex disorder characterized by symptoms such as epigastric pain, bloating, and early satiety, which significantly impact patients' quality of life. The pathophysiology of dyspepsia remains poorly understood, with multiple underlying factors including Helicobacter pylori infection, gastric motility disturbances, and visceral hypersensitivity. Modern therapeutic strategies primarily focus on acid suppression and motility enhancement, with Proton Pump Inhibitors (PPIs), H2 blockers, and prokinetic agents as standard treatments. The advent of novel therapies, such as potassium-competitive acid blockers (P-CABs) like Tegoprazan, offers promising alternatives with faster onset and longer-lasting effects. Herbal therapies, including turmeric, ginger, and licorice, have also been explored, showing potential benefits in symptom relief and gastric protection. Despite these advances, the effectiveness of treatment remains variable, and a tailored approach based on patient-specific factors is recommended. This review highlights the current treatment modalities, including both modern and traditional approaches, with a focus on pharmacological and non-pharmacological therapies for dyspepsia.
Read the paper
Related studies
- Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2018
- Improving sleep quality leads to better mental health: A meta-analysis of randomised controlled trials
- Community transmission and viral load kinetics of the SARS-CoV-2 delta (B.1.617.2) variant in vaccinated and unvaccinated individuals in the UK: a prospective, longitudinal, cohort study
- Occupation and risk of severe COVID-19: prospective cohort study of 120,075 UK Biobank participants
- Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain: a prospective observational cohort study
- Comparison of the characteristics, morbidity, and mortality of COVID-19 and seasonal influenza: a nationwide, population-based retrospective cohort study
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.