Six-month outcomes of the CODES randomised controlled trial of cognitive behavioural therapy for dissociative seizures: A secondary analysis
Abstract
Highlights • We report an unplanned secondary analysis of 6-month outcomes in the CODES trial.• 13/14 outcomes were better following CBT plus standardised medical care (SMC).• Monthly seizure frequency was significantly lower at 6 months in the CBT+SMC group.• Treatment effect sizes across outcomes were moderate-to-large at 6-month follow-ups.• Short- and longer-term evaluations are necessary to understand treatment effectiveness.
How strong is the evidence?
Evidence Hub reads this as a secondary / pooled analysis, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence.
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