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Acute portal hypertension and oesophageal varices in pregnancy

Lewis SR, Long L, Sampat K

Obstetric medicine, 2026

Abstract

Non-cirrhotic portal hypertension (PHTN) is often attributed to portal vein thrombosis and may cause serious complications. Described here is a woman with a new portal vein thrombosis in her third pregnancy, complicated by PHTN and oesophageal varices. She was managed using a multi-centre, multidisciplinary approach throughout her pregnancy and delivered a healthy baby at term via induced vaginal birth. Here, the treatment modalities available for pregnant women with PHTN and the management of complications are discussed.

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