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Posterior laryngeal web in an adult with GERD-associated globus pharyngeus: A rare case managed conservatively

Lamichhane S, Sarkar A, Maharjan S, Shrestha R, Devkota S, Pokhrel P, Bhatia H

Oxford medical case reports, 2025

Abstract

Laryngeal webs are rare structural anomalies, typically anterior in location when congenital. Posterior laryngeal webs are exceedingly uncommon and are most often acquired, with common associations including prior intubation and gastroesophageal reflux disease (GERD). GERD-induced laryngeal inflammation is a proposed mechanism for web formation due to chronic mucosal irritation and fibrosis. We present the case of a 24-year-old male with recurrent globus pharyngeus and chest discomfort, found to have a posterior laryngeal web in the absence of prior intubation or trauma. The patient was diagnosed with GERD and demonstrated marked symptomatic improvement following anti-reflux therapy. This case highlights the potential link between GERD and posterior laryngeal web formation, emphasizing the role of conservative management in select cases. Further research is warranted to explore the pathophysiological relationship between GERD and laryngeal structural changes, as well as to refine treatment strategies.

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