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Esophageal hyperkeratosis in a teenager with asthma and chronic cough complicated by nontuberculous mycobacteria pulmonary infection

Saito N, Dralyuk I, Soni PR, Lutfeali S, Guindi M, Wozniak LJ

SAGE open medical case reports, 2025

Abstract

We present a case of a 16-year-old boy with asthma referred to pediatric gastroenterology for nausea and chronic cough. Esophagogastroduodenoscopy and bronchoscopy revealed parakeratosis/hyperkeratosis in the esophagus and nontuberculous mycobacteria pulmonary infection, respectively. Presumed reflux as a unifying cause for his symptoms was confirmed with intra-esophageal pH monitoring, and he was successfully treated with a proton pump inhibitor and a four-drug antimicrobial regimen.

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