Evidence Hub

Acute Pericarditis After Percutaneous Coronary Intervention

Smman A, Raffael I

Cureus, 2025

Abstract

Pericarditis may be a complication of percutaneous coronary intervention (PCI), and should be considered as a differential for persistent chest pain following a PCI. In this report, we present a male in his 60s, who developed pericarditis after a primary PCI for an anterior ST elevation myocardial infarction (STEMI). He had an uncomplicated PCI to left anterior descending artery, and was discharged as per standard procedure 48 hours post-procedure. On that same evening, the patient re-presented to hospital with different chest pain and fever. Electrocardiogram (ECG) revealed anterior ST elevation. A provisional diagnosis of pericarditis was made in view of elevated inflammatory markers, a recent Mycoplasma infection with fevers, positron emission tomography-computed tomography (PET-CT) findings, as well as pericardial chest pain. A three-month course of colchicine was initiated. Two weeks after discharge, he was readmitted with non-resolving fevers. Echocardiogram (ECHO) and CT thorax revealed a 26mm pericardial effusion. This was not drained, as he had no signs of tamponade. He was treated as possible infective pericarditis with intravenous (IV) teicoplanin and piperacillin-tazobactam, which was stepped down to oral co-trimoxazole on discharge. Three weeks after completing the oral antibiotics, he was re-admitted again with fevers and chest pain. He was restarted on antibiotics and heart failure medications were up-titrated. He was continued on colchicine and started on…

How strong is the evidence?

Evidence Hub reads this as a case report, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

Read the paper

Related studies

Go deeper in Evidence Hub

Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.

Open this study Sign up free