Analytical Methods Developed for the Determination of Pantoprazole Sodium: Overview
Abstract
Pantoprazole sodium a substituted benzimidazole derivative is an irreversible proton pump inhibitor and was developed for the treatment of acid-related gastrointestinal disorders. As with other drugs of its class (omeprazol or lansoprazole), pantoprazole reduces gastric acid secretion through inhibition of the portion on the gastric parietal cell. Analytical methods for the determination of the active drug ingredient pantoprazole sodium are available in many manuscripts. Pantoprazole sodium, alone or in combination with other drugs, in different pharmaceutical forms, industrial wastewater, and plasma samples using spectroscopic, chromatographic, electroanalytical and thermal analysis methods have been made by many researchers analyzed. Manuscripts were identified that included analytic methods developed to analyze pantoprazole sodium alone or in the presence of other drugs included. In this review, an overview of the analytical methods developed for the determination of Pantoprazole sodium and their validation will be given.
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