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A systematic review of symptomatic outcomes used in oesophagitis drug therapy trials

NavNidhi Sharma, C Donnellan, C Preston, Brendan C. Delaney, G Duckett, Paul Moayyedi

Gut, 2004

25 citations

Abstract

Symptoms are an important outcome for measurement in clinical trials into gastro-oesophageal reflux disease, but the optimal approach to symptom assessment has not been formally evaluated. The authors conducted a systematic review to assess how reflux symptoms have been evaluated and how well these correlate with oesophagitis healing and relapse.

How strong is the evidence?

Evidence Hub reads this as a systematic review. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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