A case of Lansoprazole-associated collagenous colitis in a hemodialysis patient
Abstract
症例は81歳，男性．2008年12月に血液透析導入時よりランソプラゾールを内服していた．2009年3月より慢性の水様性下痢を認め，便ヘモグロビン検査が陽性となった．大腸内視鏡検査では上行結腸粘膜に縦走潰瘍を認め，生検組織検査で粘膜上皮直下にcollagen bandを認めた．ランソプラゾールの内服を中止することで，速やかに症状が消失したことから，ランソプラゾール関連性collagenous colitisと診断した．透析患者は消化管の易出血性のためランソプラゾールなどのプロトンポンプ阻害剤の服用率が高い．慢性下痢を呈する透析患者に遭遇した場合，ランソプラゾールの内服状況を確認した上で，当疾患を鑑別すべきである．
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