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Comparatire Study on Lansoprazole and Mosapride in Treatment of Patients with Bile—reflux Gastritis

Qin Li-yang

Chinese Journal of Trauma and Disability Medicine, 2011

5,020 participants

Abstract

Objective:To compare the efficacy of Lansoprazole and Mosapride in treatment of patients With bile-reflux gastritis.Methods:Patients,confirmed with bile reflux gastritis,were enolled in the study.Patients were randomly assigned intocontrolgroup(n=50),Lansoprazolegroup(n=50,20mgdaily),Mosapride group(n=50,1.0g three times daily)andLansoprazole combinedMosapridewith group(combination group,n=50)and treated for 8 weeks.Dyspeptic symptoms of abdominal pain,bloating,heartburn and bitter taste were observed.Results:The dyspeptic symptoms were relieved in three groups after treatment.Conclusion:Lansoprazole combined with Mosapride might be effective in the treatment of patients with bile reflux gastritis.

How strong is the evidence?

Evidence Hub reads this as a randomized trial, done in people. Its evidence level is 2 of 5 (High · randomized trial). Randomized trials of a reasonable size are the strongest single-study design. Reported size: 5,020 participants or records.

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