Synthesis and in vitro Biological Activity of Organic Charge-transfer Complexes of lansoprazole, fluconazole, gabapentin and gabalactum with Chloranilic and Picric Acids
Abstract
Novel Charge-transfer (CT) complexes were synthesized in order to determine their antimicrobial and antioxidant activity relationships to improve the efficacy. The purity of the synthesized complexes was judged by their elemental analyses, and their chemical structures were confirmed by UV-visible, FT-IR and 1H NMR spectral studies. Among the synthesized compounds, 2a and 2b showed good antimicrobial activity. Compound 1a showed moderate antioxidant activity compared to standard drug by diphenylpicrylhydrazyl (DPPH) assay method.
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