Development and validation of spectrophotometric method for the quantitative determination of lansoprazole and rabeprazole
Abstract
The article is devoted to the development and validation of methods for spectrophotometric quantitative determination of lansoprazole and rabeprazole in the substance and various prepara-tions. 96% ethyl alcohol was chosen as a common solvent. The working wavelengths for lanso-prazole were set at 285 nm, and for rabeprazole at 275 nm. The relative error of determination is ± 0.32% for “Lansil” capsules, ± 0.58% for “Rabeloc” lyophilized powder. The validation of methods for spectrophotometric quantitative determination of lansoprazole and rabeprazole in standard samples for some parameters was carried out.
Read the paper
Related studies
- The Prediction of the In Vitro Release Curves for PLGA-Based Drug Delivery Systems with Neural Networks
- Promising Ursolic Acid as a Novel Antituberculosis Agent: Current Progress and Challenges
- Proof of principle concept for the analysis and functional prediction of rare genetic variants in the CYP2C19 and CYP2D6 genes
- Fabrication, characterization, and docking studies of furosemide-loaded nanosponges using the emulsion solvent diffusion method
- The Effect of Concomitant Administration of Proton Pump Inhibitors on the Pharmacokinetics of CDK4/6 Inhibitors in Rats: Implications for the Evaluation of Hepatic and Transporter-Mediated Drug–Drug Interactions
- Mining the Metabolic Capacity of Clostridium sporogenes Aided by Machine Learning
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.