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Cost Minimization Analysis of Lansoprazole and Omeprazole in Inpatient Gastritis patients at Dirgahayu Hospital Samarinda

Safitri Safitri, Heri Wijaya, Rusdiati Helmidanora

Asian Journal of Pharmaceutical Research, 2026

Abstract

The increasing cost of health care requires an analysis that considers the aspect of economic efficiency in treatment. Gastritis is one of the diseases with a high prevalence that requires clinically effective and economically efficient therapy. This study aims to determine the minimum cost between the use of lansoprazole and omeprazole in hospitalized patients with gastritis at Dirgahayu Hospital Samarinda using the cost minimization analysis method. This study uses a pharmacoeconomic approach to identify alternative therapies with lower costs without reducing clinical effectiveness. In the pharmacoeconomic approach, the cost minimization analysis method is used to compare the costs of two health interventions that have equivalent clinical effectiveness. This study uses a quantitative study design with retrospective data collection and data are analyzed using cost minimization analysis to determine the minimum cost between the costs of lansoprazole and omeprazole treatment. Statistical methods are used to evaluate significant differences between groups. The sampling technique used is purposive sampling based on predetermined inclusion and exclusion criteria. The analysis includes fixed costs and variable costs. The results showed that patients with omeprazole therapy had the lowest cost with CMA per patient of IDR 2,495,987 compared to lansoprazole therapy with CMA per patient of IDR. 2,512,812 which had a relatively higher cost, however, there was no significant difference…

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