GAMBARAN POTENSI INTERAKSI OBAT LANSOPRAZOLE DI APOTEK BIMA 1 JEMBER ( Periode Januari SampaiMaret 2022)
Abstract
Most of the interactions between drugs will have a detrimental impact on patient therapy. Drug interactions are considered clinically important if they result in increased toxicity or reduced therapeutic efficacy. This study was conducted to analyze the potential for drug interactions in prescriptions containing the drug lansoprazole and there are 2 or more combinations at Bima 1Pharmacy based on severity. This research was conducted in the period January – March 2022. This study used a retrospective descriptive research design with sampling, namely the total sampling technique with a sample of 48 prescription sheets and analyzed using the Drug Intercation Checker on drugs.com and using a number of libraries such as Stockley's Drug Interaction 9th to determine the potential for drug interactions based on the severity and mechanism of the interaction. The results of the analysis were classified in the form of percentages. Based on the severity level, the majority of interactions were moderate (66,67%), followed by minor interactions (28,57%), and major interactions (4,76%). Judging from the many potential drug interactions, it was better to treat the potential drug interactions.
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