Histopathological and biochemical evaluation of the protective efficacy of Prunus spinosa L. extract in a rat model of indomethacin-induced gastric ulcer
Abstract
Objectives: , which has proven antioxidant, anti-inflammatory, and wound-healing properties, are unclear. Materials and Methods: fruits were administered orally at 100 mg/kg and 200 mg/kg to Wistar albino rats, with an indomethacin-induced gastric ulcer model. The ulcerous areas on the stomach surface were examined macroscopically. Tissues were examined histopathologically and biochemically. LC-HRMS revealed the phytochemical content. Results: extract by LC-HRMS. Conclusion: showed its effects in a dose-dependent manner.
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