Intention Treatment for Anomia: Investigating Dose Frequency Effects and Predictors of Treatment Response to Improve Efficacy and Clinical Translation
Abstract
Every year approximately 15,000 Veterans are hospitalized for stroke, and up to 40% of those Veterans will experience stroke-related language impairment (i.e., aphasia). Stroke-induced aphasia results in increased healthcare costs and decreased quality of life. As the population of Veterans continues to age, there will be an increasing number for Veterans living with the aphasia and its consequences. Those Veterans deserve to receive aphasia treatment designed to facilitate the best possible outcomes. In the proposed study, the investigators will investigate optimal treatment intensity and predictors of treatment response for a novel word retrieval treatment. The knowledge the investigators gain will have direct implications for the selecting the right treatment approach for the right Veteran.
Conditions: Aphasia, Stroke.
Primary outcome: Number of correctly named pictures; Number of correctly generated category members; Western Aphasia Battery; Boston Naming Test; Test of Everyday Attention; Brief Visuospatial Memory Test-Revised; Hopkins Verbal Learning Test-Revised; Digit Span Backwards; Delis-Kaplan Executive Function System (D-KEFS) Sorting; Structural MRI scan; Functional MRI scan.
Enrollment: 32 participants.
How strong is the evidence?
Evidence Hub reads this as a clinical trial, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 32 participants or records.
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