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Evaluating the Robustness of Retrieval-Augmented Generation to Adversarial Evidence in the Health Domain

Shakiba Amirshahi, Amin Bigdeli, Charles L. A. Clarke, Amira Ghenai

arXiv, 2025

Abstract

Retrieval augmented generation (RAG) systems provide a method for factually grounding the responses of a Large Language Model (LLM) by providing retrieved evidence, or context, as support. Guided by this context, RAG systems can reduce hallucinations and expand the ability of LLMs to accurately answer questions outside the scope of their training data. Unfortunately, this design introduces a critical vulnerability: LLMs may absorb and reproduce misinformation present in retrieved evidence. This problem is magnified if retrieved evidence contains adversarial material explicitly intended to promulgate misinformation. This paper presents a systematic evaluation of RAG robustness in the health domain and examines alignment between model outputs and ground-truth answers. We focus on the health domain due to the potential for harm caused by incorrect responses, as well as the availability of evidence-based ground truth for many common health-related questions. We conduct controlled experiments using common health questions, varying both the type and composition of the retrieved documents (helpful, harmful, and adversarial) as well as the framing of the question by the user (consistent, neutral, and inconsistent). Our findings reveal that adversarial documents substantially degrade alignment, but robustness can be preserved when helpful evidence is also present in the retrieval pool. These findings offer actionable insights for designing safer RAG systems in high-stakes domains by…

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