Investigating nutrient intake during use of glucagon-like peptide-1 receptor agonist: a cross-sectional study
Abstract
Background Glucagon-like peptide-1 receptor agonist (GLP-1RA) pharmaceutical interventions have advanced medical treatment for obesity, yet little is known about nutrient intake while using a GLP-1RA. The purpose of this study was to compare nutrient intake while using a GLP-1RA to the Dietary Reference Intakes (DRI). Methods A cross-sectional study was conducted in a sample of participants who had been using GLP-1RA for at least one month (N = 69). Participants answered online survey questionnaires and completed a 3-day food record. Descriptive statistics (means, standard deviations) were calculated for all participant demographic characteristics and average 3-day nutrient intakes. Average 3-day nutrient intakes were compared to the DRI using 95% confidence intervals (CI). A Bonferroni correction applied accepted significance at p ≤ 0.00156. One-way ANOVA analysis was conducted to compare the self-reported MyPlate servings to recorded servings from the 3-day food record. Results Compared to the DRI reference values, participants consumed adequate amounts of B-vitamins, copper, phosphorus, selenium, and zinc. Participants had insufficient intakes of several key nutrients below the DRI, including fiber (14.5 g; CI: 12–17), calcium (863 mg; CI: 756–970), iron (12.1 mg; CI: 11–13), magnesium (266 mg; CI: 236–297), potassium (2,186 mg; CI: 1,969–2,402), choline (305 mg; CI: 268–342), vitamin A (560 mcg RAE; CI: 469–651), vitamin C (51 mg; CI: 41–61), vitamin D (4 mcg; CI: 3–5),…
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