Exploring the application boundaries of LLMs in mental health: a systematic scoping review
Abstract
Background: The rapid evolution of large language models (LLMs) has ushered in a new era of artificial intelligence (AI) with unprecedented capabilities in understanding and generating human-like text. This progress has sparked a burgeoning interest in applying LLMs across diverse fields, including healthcare. However, the use of LLMs in mental health remains a complex area that demands rigorous investigation. This systematic scoping review aims to explore the current landscape of LLM applications in mental health, identify key research trends and gaps, and delineate the ethical and practical boundaries, thereby providing a comprehensive framework for future research and clinical practice.
Methods: This study adheres to the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews) guidelines. A comprehensive search was conducted across eleven databases (Web of Science, Scopus, PubMed, Medline, CINAHL, Cochrane, ACM Digital Library, IEEE Xplore, ScienceDirect, APA PsycInfo, and Google Scholar). A total of 29 articles were ultimately included in the study.
Results: The application of LLMs in mental health is strategically focused on high-throughput screening and clinical augmentation. The application landscape is characterized by domain specialization, with the focus shifting from general models to specialized BERT models to achieve higher clinical accuracy, particularly for high-prevalence disorders such as depression and…
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Evidence Hub reads this as a systematic review. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
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