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Retrieval-Augmented Generation for Survival Analysis in Cancers

Jyothi Vaidyanathan

2025

Abstract

Healthcare is one of the most important fields that benefits from advancements in Artificial Intelligence (AI). From classic models like linear regression to cuttingedge transformers, AI is applied across various healthcare subdomains, such as drug discovery, predictive analytics, and personalized medicine, to name a few. These techniques enable medical practitioners to make more informed decisions, significantly improving both the speed and accuracy of diagnoses and treatments. Machine learning has played a transformative role in oncology, especially in areas like early detection, diagnosis, treatment planning, and patient monitoring, by analyzing medical images, clinical information, genomic data, sensor information. Our research aims to develop a solution for predicting cancer patient survivability using an emerging approach in AI, called Generative AI. Specifically, we will leverage Large Language Models, a powerful subset of Generative AI, including other facets of AI, namely Natural Language Processing (NLP), Machine Learning (ML), and Rule based systems. We also look into how Retrieval Augmented Generation can be used to derive insights from larger datasets, followed by evaluation of the responses given by LLMs, using the LLM as a Judge approach. This research enables us to capture insights from unstructured data that can go unnoticed in traditional machine learning pipelines. By integrating generative models with retrieval mechanisms, our goal is to deliver more…

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