Ensuring trustworthy AI assisted guideline development for clinical practice
Abstract
Li et al. introduce Quicker, an agentic large language model system that drafts clinical guideline recommendations through a GRADE-based workflow. Building on gaps in the authors' own evaluation, we propose safeguards for trustworthy use: verifiable, design-aware evidence bundles with explicit scope; calibrated, uncertainty-aware deferral; targeted human validation and modular quality gates; and governance against contamination and over-reliance. Trustworthiness, however, is necessary but not sufficient for clinician trust.
Read the paper
Related studies
- Knowledge Management Perspective of Generative Artificial Intelligence
- Navigating Generative Artificial Intelligence Promises and Perils for Knowledge and Creative Work
- Characterizing the evolving research on enterprise content management
- Large language models and multimodal foundation models for precision oncology
- From Generative AI to Extended Reality: Multidisciplinary Perspectives on the Challenges, Opportunities, and Future of Educational Computing
- Generative Artificial Intelligence: A New Engine for Advancing Environmental Science and Engineering
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.