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Successful use of dupilumab in recalcitrant pediatric atopic dermatitis-like graft-versus-host disease: A case series

Lina Belmesk, Afshin Hatami, Julie Powell, V. Kokta, J. Coulombe

JAAD Case Reports, 2023

12 citations

Abstract

in an 8-year-old boy who presented with multiple papules, nodules, and lichenified plaques ( A ). Significant improvement was observed after 8 weeks of dupilumab treatment, with complete resolution of the lesions ( B ). As a result, the patient was able to discontinue his other immunosuppressants used for treating his cutaneous GvHD. AD-like , Atopic dermatitis-like; GvHD , graft-versus-host disease.

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Evidence Hub reads this as a case series, done in people. Its evidence level is 5 of 5 (Very low · case / narrative / animal / in vitro / in silico). Case reports, narrative reviews, and animal, cell or computer-model studies give the weakest evidence for human health.

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