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AI unleashed: A meta-analysis transforming radiological insights in diagnosing abdominal infections

Rosa Alba Pugliesi, A. Papachristodoulou, K. Ben Mansour, Nour Maalouf, Roua Ben Ayed, Jonas Apitzsch

Comput. Biol. Medicine, 2026

1 citation

Abstract

INTRODUCTION

Artificial intelligence (AI)-based imaging modalities are next-generation diagnostic devices for abdominal infections that promise to provide enhanced diagnostic speed and accuracy. This systematic review and meta-analysis critically analyze the diagnostic accuracy of AI-assisted imaging modalities, including for appendicitis, pneumoperitoneum, and cholecystitis, to present a balanced estimate of their clinical utility.

METHODS

A systematic literature search was undertaken in PubMed, Scopus, and Cochrane databases to search for studies that assessed the diagnostic accuracy of AI-based imaging modalities for abdominal infections. Eleven studies were included based on the inclusion criteria, and data were pooled for analysis. Diagnostic performance was measured by estimating sensitivity, specificity, likelihood ratios, diagnostic odds ratio (DOR), and area under the curve (AUC) using a random-effects model. Subgroup analyses were done to investigate the effect of infection type on diagnostic accuracy.

RESULTS

AI-assisted imaging demonstrated an overall sensitivity of 0.891 (95% CI: 0.824-0.944) and specificity of 0.860 (95% CI: 0.784-0.922) for diagnosing abdominal infections. Subgroup analysis revealed that AI-aided computed tomography (CT) exhibited a sensitivity of 0.902 (95% CI: 0.850-0.948), while ultrasound (US) showed a sensitivity of 0.864 (95% CI: 0.792-0.922). The highest AUCs were observed for pneumoperitoneum (0.985) and appendicitis (0.947),…

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