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CTI_Pulseq Tutorial Dataset: Raw Phantom Diffusion MRI Data for Correlation Tensor Imaging (CTI)

Joāo S. Periquito

Zenodo (CERN European Organization for Nuclear Research), 2026

Abstract

This dataset contains raw MRI scanner data (TWIX .dat format) from a Correlation Tensor Imaging (CTI) acquisition, provided as a small tutorial dataset for CTI_Pulseq — an open-source PyQt5 GUI covering the full CTI workflow: pulse sequence generation (Pulseq/pypulseq), image reconstruction, and CTI model fitting. What is CTI? Correlation Tensor Imaging is a diffusion MRI technique using double diffusion encoding (DDE) — two diffusion-sensitizing gradient pairs played within one echo — to decompose diffusional kurtosis into isotropic, anisotropic, and microscopic sources, going beyond conventional DTI/DKI (Henriques, Jespersen & Shemesh, 2021, NeuroImage). Acquisition protocol. A multi-slice, GRAPPA-accelerated, partial-Fourier spin-echo EPI readout, repeated across 4 diffusion-encoding "sets" that differ in how the total b-value is split between the two DDE gradient pairs and their relative orientation: Set b1 b2 Orientation Role 1 1500 s/mm² 0 — single diffusion encoding (SDE) reference 2 750 s/mm² 750 s/mm² parallel symmetric parallel DDE 3 750 s/mm² 750 s/mm² perpendicular symmetric perpendicular DDE 4 375 s/mm² 375 s/mm² parallel parallel DDE, lower b Each set: 45 diffusion directions, FOV 256 mm, 72×72 matrix (~3.6 mm in-plane resolution), 3× 5 mm slices, TR 10 s, TE ≈ 152 ms, partial-Fourier factor 0.75, GRAPPA R=2 (24 ACS lines), δ1=δ2=28 ms, Δ1=Δ2=34 ms. 48 repetitions per set (1 navigator + 2 b0 blip-up/down + 45 directions), ~8 minutes scan time per set. Files.…

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