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Pre and post treatment MRI and radiotherapy plans of patients with glioblastoma: the CFB-GBM cohort (CFB-GBM)

Noémie N. Moreau, Alexandre G. Leclercq, Alexis Desmonts, Yoann Poirier, Aurélie Dubru, Laura Guillemette, Pascal Lecoeur, Kévin Lemasson et al.

The Cancer Imaging Archive, 2025

264 participants

Abstract

Patients included in the “CFB-GBM” dataset correspond to 264 patients with glioblastoma involved in the clinical routine. Pre-treatment MRI (t0) was acquired for all patients. The sequences, such as T1Gd, T1 anatomical, T1 gradient echo, T2 anatomical, T2-FLAIR, T2* or diffusion weighted imaging, were included, depending on their availability. In addition, post-treatment MRI at different times (t1 and t2) were obtained, if available. For some patients, we have also included treatment imaging, such as CTscan, radiotherapy dose and tumor delineation. Clinical data : survival, age, WHO status, gender, height, weight, IDH status and MGMT methylation. Surgery criteria, RT dose and machine, fractions. CTscan machine, MRI machine, and the delay between the t1 and t2 MRI and t0 MRI. Potential research applications of the dataset: AI model development for: Outcome prediction [1] Tumor segmentation and evolution after treatment MRI generation Spatial analysis of the tumor evolution using RT dose by a pixel to pixel analysis.

How strong is the evidence?

Evidence Hub reads this as a cohort study, done in people. Its evidence level is 3 of 5 (Moderate · trial / cohort / secondary analysis). Trials without a large randomized design, cohorts and secondary analyses give moderate evidence. Reported size: 264 participants or records.

How the five levels of evidence work. The level is assigned automatically from the abstract and can be wrong, so check the paper.

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