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Editorial for “Accelerating Cardiac Diffusion Imaging With a U‐Net Based Model: Towards Single Breath‐Hold”

G. Strijkers

Journal of Magnetic Resonance Imaging, 2022

744 participants

Abstract

Editorial for “Accelerating Cardiac Diffusion Imaging With a U-Net Based Model: Towards Single Breath-Hold” The heart is a highly sophisticated muscular organ whose unique set of interconnected features, involving anatomy, fiber architecture, electrical activity, metabolism, contractility, and hemodynamics, enable it to adapt quickly to a wide range of physiological demands and usually guarantee a healthy function during a person’s life. In case of heart disease, physicians have a number of state-of-the-art tools to their disposal to diagnose changes in cardiac structure–function relationships. These include blood tests, various noninvasive imaging modalities (eg echocardiography, MRI, and CT) to probe anatomical, functional, and hemodynamic alterations, electrophysiology tests, as well as cardiac catheterization and coronary angiography to diagnose blocked arteries and assess intraventricular hemodynamic conditions. Despite progress in imaging technology, however, one highly important aspect of the structure–function relationships of the heart has proven notoriously difficult to capture, which is the architectural arrangement of the muscle fibers in the myocardial walls. This muscle fiber arrangement is essential for understanding healthy cardiac dynamics and how failure occurs due to disease. Although the human heart has been studied extensively using dissection and imaging techniques, ex vivo characterization of muscle architecture obviously cannot report on how the…

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