Editorial for “Differentiating benign and malignant breast lesions in diffusion kurtosis MRI: Does the averaging procedure matter?”
Abstract
Editorial for “Differentiating benign and malignant breast lesions in diffusion kurtosis MRI: Does the averaging procedure matter?” Breast cancer is the most common malignant tumor in women. Advances in the early diagnosis and treatment of breast cancer in recent years have resulted in improvements in the survival rate. Thus, all interest and efforts in breast cancer have been directed toward early diagnosis and treatment. The dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is widely used in the diagnosis, local staging, and treatment evaluation with neoadjuvant chemotherapy of breast cancer. Furthermore, it is recommended as a screening test for females with ≥20% to 25% lifetime risk of disease development. The Breast Imaging Reporting and Data System (BI-RADS) is often used in breast MRI. However, BI-RADS is subjective and qualitative. In addition, conventional breast MRI requires a contrast injection. Diffusion-weighted imaging (DWI) is a contrast-free functional MRI technique incorporated into clinical practice. It can improve the diagnostic accuracy of MRI in breast cancer. DWI analysis assumes that water molecules follow the Gaussian distribution, such that water molecules diffuse without any restriction. It yields a quantitative parameter, namely, the apparent diffusion coefficient (ADC). However, the diffusion of water molecules in the breast is not Gaussian due to the complexity of the fibroglandular tissue and the microenvironment of the cancerous…
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