Efficacy of thyroid isthmusectomy and its outcomes in patients with single isthmic papillary thyroid carcinoma: a single-center observational study
Abstract
Background; Despite the total thyroidectomy is recommended for isthmic papillary thyroid carcinoma (PTC), the gold standard surgery is not well-known. We aimed to investigate the efficacy of isthmusectomy and its outcomes in the treatment of isthmic PTC. Methods; Allpatients with single isthmic PTC and underwent total thyroidectomy with or without central neck dissection (CND) were included in the study. Patients with cervical lymph node metastasis and neck extension or patients with their cancer in another place were omitted from the study. Included patients were subdivide into 3 groups; total thyroidectomy, lobectomy with isthmusectomy, and isthmusectomy. Clinical and pathologic data and surgical outcomes were collected. Results: Among the included 121 patients, 28 were males and 93 were females. Total thyroidectomy, isthmusectomy, and lobectomy with isthmusectomy were conducted in 70 (57.8%), 11 (9.1%), and 40 (33.1%), patients, respectively. Patients with total thyroidectomy showed increased postoperative hypoparathyroidism than patients with lobectomy and isthmusectomy. On the other hand, there were no significant differences in the recurrence rate or the survival between the 3 groups. Conclusion; Total thyroidisthmusectomy may be helpful in the surgical management of small single isthmic PTC. Further studies are needed to verify this result.
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