Sparfloxacin and the fluoroquinolones : a review of classification, antibacterial activity, mechanism of action, pharmacokinetic properties, tolerability and pharmaceutical perspectives
Abstract
Foi realizada uma revisão na literatura sobre as quinolonas, classe antibacteriana que possui amplo espectro de ação, enfocando, principalmente, o esparfloxacino, fluorquinolona de terceira geração que possui potente atividade contra bactérias Gram-positivas, como Streptococcus pneumoniae e Staphylococcus auieus inclusive cepas metilina resistentes (MRSA), bactérias Gram-negativas, anaeróbios, Legionella spp, Mycoplasma spp, Chlamydia spp e Mycobacteríum spp.
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