Prevalence and Antimicrobial Resistance of Pseudomonas aeruginosa Recovered from Respiratory and Urinary Specimens in a Lebanese Hospital (2020-2025)
Abstract
Background: Respiratory tract infections (RTIs) and urinary tract infections (UTIs) are among the most common infections in humans. It is estimated that millions of deaths occur each year worldwide due to these infections. Pseudomonas aeruginosa (P. aeruginosa), in particular, represents a public health threat since it has a high ability to acquire resistance to different antibiotic classes. The aim of this study was to determine the prevalence and antimicrobial resistance patterns of P. aeruginosa isolates from patients with RTIs and UTIs in Lebanon.
Methods: This retrospective study was performed during 2020-2022 and 2024-2025. Samples were collected from both inpatients and outpatients, where identification and isolation of bacteria were performed along with antibiotic susceptibility testing.
Results: The overall prevalence of P. aeruginosa isolates in RTI cases over the study period was 10.9%, and that of UTI cases was 1.3%. The general antimicrobial resistance profile of P. aeruginosa isolates from RTI and UTI cases showed the highest resistance for Piperacillin-Tazobactam and Aztreonam, respectively. For RTIs, antibiotic resistance decreased from 48.1% in 2020 to 36.7% in 2025 and increased from 16.7% to 19.4% for UTIs.
Conclusions: According to our research, P. aeruginosa with low antibiotic susceptibility is frequently found in isolated samples, highlighting the significant challenge in treating severe infectious illnesses. To choose focused and efficient antibiotic…
Read the paper
Related studies
- Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes
- Mutation supply and relative fitness shape the genotypes of ciprofloxacin-resistant Escherichia coli
- Genomic Survey of E. coli From the Bladders of Women With and Without Lower Urinary Tract Symptoms
- Characterization of cefotaxime-resistant urinary Escherichia coli from primary care in South-West England 2017–18
- Fitness cost constrains the spectrum of marR mutations in ciprofloxacin-resistant Escherichia coli
- Emerging evidence-based innovative approaches to control catheter-associated urinary tract infection: a review
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.