Prevalence, antimicrobial resistance, and risk factors of bacterial urinary tract infections among asymptomatic diabetes mellitus patients in Bahir Dar, Ethiopia
Abstract
Introduction: Diabetes mellitus associated with urinary tract infections. This study aimed to determine the prevalence of bacterial infection of urinary tract, assess antimicrobial resistance, and associated factors among asymptomatic diabetic patients attending Felege Hiwot Comprehensive Specialized Hospital, Bahir Dar, northwestern Ethiopia.
Methods: An institution-based cross-sectional study was conducted from January to March 2025 among 248 diabetic patients. Sociodemographic and clinical data were collected using a structured questionnaire. Data were entered into EPI data 3.1 and exported to SPSS v.26. Bivariate and multivariable logistic regression analyses were used to identify factors associated with bacterial infection of urinary tract, with p < 0.05 considered statistically significant.
Results: Of the 248 study participants, 63 (25.4%) had bacterial infection of urinary tract. Gram-negative bacteria predominated, with Escherichia coli (38.1%), Klebsiella pneumoniae (20.6%), and Acinetobacter baumannii (11.1%) being the most common isolates. High resistance was observed to commonly used antibiotics, including ampicillin, amoxicillin-clavulanate, chloramphenicol, and co-trimoxazole. In multivariable analysis, age 19-60 years (AOR = 3.95; 95% CI: 1.55-10.08), divorced marital status (AOR = 3.05; 95% CI: 1.02-9.09), prior history of UTI (AOR = 2.20; 95% CI: 1.12-4.33), and longer duration of diabetes (6-10 years: AOR = 3.85; >10 years: AOR = 5.50) were significantly…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 248 participants or records.
Read the paper
Related studies
- Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes
- Mutation supply and relative fitness shape the genotypes of ciprofloxacin-resistant Escherichia coli
- Genomic Survey of E. coli From the Bladders of Women With and Without Lower Urinary Tract Symptoms
- Characterization of cefotaxime-resistant urinary Escherichia coli from primary care in South-West England 2017–18
- Fitness cost constrains the spectrum of marR mutations in ciprofloxacin-resistant Escherichia coli
- Emerging evidence-based innovative approaches to control catheter-associated urinary tract infection: a review
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.