The systematic Review of Quinolones Resistance of Escherichia coli Isolated from Urinary Tract Infections in Iran over the Last Ten Years (2001-2011)
Abstract
Aims: Urinary tract infection (UTI) is one the most common bacterial infection and Escherichia coli (E. coli) has been isolated from the majority of UTI cases. On the other hand, the rate of UTIs caused by quinolones resistant E. coli is increasing worldwide. We aimed to perform a systematic review of quinolones resistance of E. coli isolated from urinary tract infections in Iran over last ten years. Review Article Akya et al.; ARRB, 6(4): 234-244, 2015; Article no.ARRB.2015.081 235 Methodology: In this study the data of 53 cross-sectional studies from 2001 to 2011 on quinolones resistance of E. coli isolated from UTIs in 22 cities of Iran was collected. The data was statistical analyzed using SPSS version 18 and Stata software. Results: Of 53 studies, 44, 41, 8 and 6 studies tested ciprofloxacin, nalidixic acid, norfloxacin and ofloxacin, respectively. Majority of studies, 31(58.5%), was done on out-patients. For susceptibility testing of isolates, 49 and 4 of studies used disk diffusion and E test method, respectively. Forty six of studies (86.8%) used mid-stream urinesample, while the rest used other methods for sampling including catheter, suprapubic aspiration and urine bag. Overall resistance for nalidixic acid, ciprofloxacin, norfloxacin and ofloxacin were 42.3%, 28.2%, 48.5% and 24.1%, respectively. The results of most studies were significantly heterogenic (P<0.001). Conclusion: Results indicated the resistance to quinolones including ciprofloxacin, norfloxacin and…
How strong is the evidence?
Evidence Hub reads this as a systematic review. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
Read the paper
Related studies
- Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes
- Mutation supply and relative fitness shape the genotypes of ciprofloxacin-resistant Escherichia coli
- Genomic Survey of E. coli From the Bladders of Women With and Without Lower Urinary Tract Symptoms
- Characterization of cefotaxime-resistant urinary Escherichia coli from primary care in South-West England 2017–18
- Fitness cost constrains the spectrum of marR mutations in ciprofloxacin-resistant Escherichia coli
- Emerging evidence-based innovative approaches to control catheter-associated urinary tract infection: a review
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.