PP-004 Antimicrobial resistance and risk factors for urinary tract infection due to ciprofloxacin-resistant Escherichia coli in Rwanda
Abstract
Background: Escherichia coli (E.coli) is one of the most commonly isolated microorganisms in clinical specimens, which cause many illness in human, the most important of which is urinary tract infection.It can also produce bacteremia, gallbladder and biliary tract, gastrointestinal and wound infection.Although E. coli is known as an antibiotic-sensitive bacterium, its resistance has been increased during past decade.The aim of this study is to determine the antibiotic resistance pattern of E. coli, according to kind of antibiotic, kind of the specimen, and the hospital where the test has been done.Methods: This study performed on 300 cultured specimens, whit positive result from the viewpoint of E. coli on the labs of pastor hospitals and central laboratory in Bam city during the 2007 2008.The information was first collected by referring to the mentioned labs, and completing questionnaire, then the data was analyzed with the software Spss, using chi-square test and extended fishers exact test.Results: In this study, sensitivity of E. coli was at the highest rate to Ciprofloxacin (59.3%),Ceftriaxone (36.3%) and Ceftizoxime (27%), and the highest rate of resistance was to Gentamicin (88.7%) and Nalidixic acid (84.7%).Conclusion: Finally on the basis of this study and as compared with the previous study done, and also to all articles mentioned, the resistance of E. coli to antibiotic must be reviewed every several years and the physicians must be award of them. PP-002 Effects…
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