Risk Factors for Ciprofloxacin and Gentamycin Resistance among Gram Positive and Gram Negative Bacteria Isolated from Community-Acquired Urinary Tract Infections in Benghazi City
Abstract
Urinary tract infections (UTIs) are a severe public health problem caused by a range of pathogens. The aims of the study were to investigate the prevalence of urinary tract infection and to see the pattern of Ciprofloxacin and Gentamycin susceptibility against uropathogens in Benghazi city. The study took place between 2021 April and October 2021. In-vitro antibacterial activity and resistance patterns of these two well-known antibiotics were studied and compared using the disk diffusion method. Laboratory reports and clinical data of patients with a positive urine culture (≥105 CFU/mL) were included in the study. Ciprofloxacin and gentamycin were tested against fourteen common bacterial pathogens, isolated from clinical samples of patients from Benghazi city Libya. A total of isolates were detected in 264 (75.4%) samples. Out of these, 75.4% were female and 24.6% were male. The majority of the study participants were in the age range of between 36-53 years (33.7%). The Increased bacterial resistance to ciprofloxacin has been shown. Most strains of E. coli and Staph aureus were resistant to ciprofloxacin and sensitive to gentamycin thereby showing that gentamycin is more effective than ciprofloxacin. This study showed that E. coli followed by staph aureus and K. pneumonia were the predominant uropathogen of UTIs in this geographical area. Most of the uropathogens were susceptible to Ciprofloxacin. The results showed that there is an alarming subject of resistance to…
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