Prevalence of Enterobacterales Producing Extended-Spectrum Beta-Lactamases According to One Health Approach in Burkina Faso: A Systematic Review with Meta-Analysis
Abstract
Background: Antimicrobial resistance (AMR) represents an important public health challenge worldwide. Given the significant and interdependent human, animal and environmental dimensions of this resistance, a 'One Health' approach is necessary to combat it. However, its extent remains poorly known and understood in resource-limited settings. This study aims to describe the current prevalence of antibiotic resistance and extended-spectrum β-lactamase (ESBL)-producing Enterobacterales species according to One Health approach in Burkina Faso.
Methods: PubMed, Hinari, African Journal Online, Scopus and Google Scholar were the bibliographic databases used for screening of the relevant articles according to the reporting elements for systematic reviews and meta-analyses (PRISMA). The meta-analysis was performed using the statistical analysis R software version 4.2.3 (2023).
Results: A total of 24 research articles were included in this systematic review and meta-analysis. E. coli, Klebsiella spp., Enterobacter spp. and Salmonella spp. were the most frequently reported bacteria from at least two sources. The environment had the highest rate of ESBL-producing Enterobacterales (60.01%). The highest proportion of ESBL production was recorded for E. coli in all sources (64.92%).
Conclusion: Our study showed a significant cluster prevalence of ESBL Enterobacterales species from all sources, with the highest prevalence found in the environment. Strong resistance to commonly used…
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Evidence Hub reads this as a meta-analysis, done in people. Its evidence level is 1 of 5 (Highest · pooled evidence). Pooled evidence from several studies sits at the top of the evidence pyramid.
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