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Antimicrobial susceptibility and risk factors of asymptomatic bacteriuria among pregnant women attending antenatal care at public health facilities in Debre Markos town, Northwest Ethiopia

Geremew M, Kebede D, Fenta A, Demeke G, Toru M

BMC microbiology, 2026

Abstract

BACKGROUND: In pregnant women, asymptomatic bacteriuria is a public health problem. Untreated asymptomatic bacteriuria is the primary cause of cystitis and pyelonephritis, which increase prenatal mortality and morbidity. Limited research has been conducted on asymptomatic bacteriuria in our study setting. Thus, this study aimed to assess antimicrobial susceptibility and risk factors of asymptomatic bacteriuria among pregnant women who attended antenatal care at public health facilities in Debre Markos town, Northwest Ethiopia.

METHODS: Using a consecutive convenience sampling technique, an institutionally based cross-sectional study was carried out in Debre Markos town's health facilities between May 1, 2023, and July 30, 2023. Pretested structured questionnaires were used to collect clinical and sociodemographic data. Additionally, a sterile container was used to collect the midstream urine sample, which was then inoculated onto sheep blood agar, MacConkey agar (MAC), and cysteine-lactose-electrolyte-deficient agar (CLED). Gram stain, biochemical tests, and colony morphology were used to identify and characterize the isolates. On Mueller-Hinton agar (MHA), the disk diffusion method was used to determine the antimicrobial susceptibility pattern. EpiData 3.0 was used to enter the data. Finally, bivariable and multivariable logistic regression was performed via SPSS version 23 to identify related factors, with a P value < 0.05 being deemed statistically significant.

RESULTS:…

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Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.

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