Potential of Kecombrang (Etlingera elatior) Flower Ethanol Extract as an Anti-Bacterial for Escherichia coli and Pseudomonas aeruginosa in Urinary Tract Infection Patients
Abstract
Pseudomonas aeruginosa and Escherichia coli are the two bacteria that produce one of the most prevalent urinary tract infections (UTIs). The rising resistance to antibiotics in these bacteria has led to the need for alternative treatments. Using natural materials, such as torch ginger flowers (Etlingera elatior), which are known to possess potent antibacterial chemicals, is one such option. This study aimed to determine the effectiveness of ethanol extract of torch ginger flower against Escherichia coli and Pseudomonas aeruginosa, and to compare its performance with ciprofloxacin as a standard control. The study was designed using a cross-sectional experimental method. The disk diffusion method on Mueller-Hinton Agar was used to assess the extract's antibacterial activity after it was made by macerating it with 70% ethanol. With an average inhibition zone of 7.8 mm against Escherichia coli and 8 mm against Pseudomonas aeruginosa at a 100% concentration, the findings demonstrated the antibacterial activity of Etlingera elatior's ethanol extract. These inhibition zones, however, were much smaller than those of ciprofloxacin, which had respective measurements of 10 mm and 34 mm. Significant differences between the extract concentrations were found by statistical analysis using the Kruskal-Wallis and Mann-Whitney tests (p < 0.05). In conclusion, the ethanol extract of torch ginger flower shows potential antibacterial activity against UTI-causing bacteria, although its…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
Read the paper
Related studies
- Horizontal gene transfer in the human gastrointestinal tract: potential spread of antibiotic resistance genes
- Mutation supply and relative fitness shape the genotypes of ciprofloxacin-resistant Escherichia coli
- Genomic Survey of E. coli From the Bladders of Women With and Without Lower Urinary Tract Symptoms
- Characterization of cefotaxime-resistant urinary Escherichia coli from primary care in South-West England 2017–18
- Fitness cost constrains the spectrum of marR mutations in ciprofloxacin-resistant Escherichia coli
- Emerging evidence-based innovative approaches to control catheter-associated urinary tract infection: a review
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.