Clinical spectrum, antibiotic sensitivity, and clinical outcome of urinary tract infection in the pediatric age group: A cross-sectional study
Abstract
Background: Urinary tract infection (UTI) is a common pediatric bacterial infection; delayed diagnosis and antimicrobial resistance increase complications and treatment challenges. The objective of this study is to evaluate the clinical profile, bacteriological spectrum, antibiotic sensitivity patterns, and clinical outcomes of urinary tract infections in children.
Methods: This hospital-based cross-sectional study was conducted in the Department of Pediatrics, J.K. Lone Mother and Child Hospital from October 2024 to January 2026. A total of 83 children aged 6 months to 18 years with culture-confirmed UTI were included. Urine samples were collected under aseptic precautions using clean-catch midstream collection, catheterization, or urine collection bags as appropriate. Samples were processed using semi-quantitative culture techniques on CLED agar. Antibiotic susceptibility testing was performed using the Kirby–Bauer disk diffusion method according to CLSI guidelines.
Results: Among 83 culture-positive cases, females constituted 59% and males 41%. Fever (85.5%) was the most common presenting symptom, followed by abdominal pain (54.2%) and increased frequency of micturition (30.1%). Escherichia coli (E. coli) was the predominant pathogen (66.3%), followed by Klebsiella species (19.3%). Nitrofurantoin and Fosfomycin showed high sensitivity among oral antibiotics, whereas Fosfomycin and Imipenem demonstrated maximum sensitivity among injectable agents. High resistance was…
How strong is the evidence?
Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 83 participants or records.
Read the paper
Related studies
- Association of lower urinary tract symptoms and OAB severity with quality of life and mental health in China, Taiwan and South Korea: results from a cross-sectional, population-based study
- Ten-Day Quadruple Therapy Comprising Low-Dose Rabeprazole, Bismuth, Amoxicillin, and Tetracycline Is an Effective and Safe First-Line Treatment for Helicobacter pylori Infection in a Population with High Antibiotic Resistance: a Prospective, Multicenter, Randomized, Parallel-Controlled Clinical Trial in China
- The Role of the NLR and PLR in Urinary Tract Infection
- Threat of Antimicrobial Resistance among Pilgrims with Infectious Diseases during Hajj: Lessons Learnt from COVID-19 Pandemic
- Leclercia adecarboxylata urinary tract infection in a patient with bladder cancer and recurrent hematuria
- A Case Series of Staphylococcus lugdunensis Infection in Cancer Patients at an Academic Cancer Institute in the United States
Go deeper in Evidence Hub
Evidence Hub adds a study data sheet (design, sample size, evidence level, key numbers), an AI summary and a chat grounded in the paper's text.