Patterns of Antibiotic Resistance in Urinary Tract Infection: Insights from a Tertiary Care Hospital in Bangladesh
Abstract
Background: Urinary tract infections (UTIs) are among the most common bacterial infections encountered in both community and hospital settings, affecting individuals across all age groups. They pose a significant health burden, particularly in developing countries like Bangladesh, where poor hygiene practices, irrational antibiotic use, and limited access to healthcare contribute to their prevalence. This study aims to assess the current resistance profiles of uropathogens isolated from patients with UTIs at a tertiary care hospital in Bangladesh. Methods: This cross-sectional study was conducted at Department of Medicine, Shaheed M Monsur Ali Medical College, Sirajganj, Bangladesh, from July 2024 to January 2025. A total of 108 midstream urine samples were collected from patients clinically diagnosed with urinary tract infections (UTIs), following standard aseptic procedures. Data were analyzed using SPSS version 25.0. Result: In this study of 108 UTI cases, Escherichia coli emerged as the most prevalent uropathogen (62%), followed by Klebsiella pneumoniae (16.7%) and Proteus species (7.4%). Females were more commonly affected (68.5%) than males. Antibiotic susceptibility testing revealed high resistance to ampicillin (85.2%), ceftriaxone (63%), and ciprofloxacin (59.3%), while nitrofurantoin (74.1%) and imipenem (88.9%) showed the highest sensitivity. Multidrug resistance was observed in 53.7% of isolates, particularly among E. coli and Klebsiella species. Conclusion: This…
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Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause.
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