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Bacterial urinary tract infection and antibiotic sensitivity pattern among type II diabetic patients – A cross-sectional study from tertiary care teaching hospital in Central Lahore

K. Muneer, K. Fatima, Naheed Hashmat, S. Humayun, Qaiser Pervaiz, Saim Maqsood

2020

215 participants

Abstract

Background: Diabetes mellitus is the fifth leading cause of death in developed countries. Risk of infections is increased in diabetic patients with urinary tract being the most common site of infection. Worldwide, the prevalence of urinary tract infections (UTI) is estimated to be around 150 million persons per year. UTI exhibit a poorer prognosis in patients of type 2 diabetes mellitus (T2DM) due to a compromise in their immune status in addition to emerging antimicrobial resistance due to widespread use of antimicrobial agents. This study aims to determine frequency of common bacterial pathogens causing UTI and antibiotic sensitivity pattern among type 2 diabetic patients. This may help to guide physicians regarding appropriate management of UTI in the local population to avoid multidrug resistance. Patients and methods: This cross sectional study involved 215 type 2 diabetic patients admitted to Medical Unit-III of Sir Ganga Ram hospital, Lahore from 01-12-2016 to 31-05-2017. Type 2 adult diabetic patients (diagnosed for at least 1 year) of age 40-80 years, either male or female performed as baseline investigation at admission were included in the study. Further urine samples were obtained (clean catch midstream urine 10cc in two wide mouth sterile screw capped plastic jars) before starting treatment. Samples were sent for microscopy and culture. Culture results and antibiotic sensitivities were recorded. Data was analyzed using SPSS for windows version 23.0. Categorical…

How strong is the evidence?

Evidence Hub reads this as a cross-sectional, done in people. Its evidence level is 4 of 5 (Low · observational). Observational designs can show an association but not prove cause. Reported size: 215 participants or records.

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